Toxicity test of Kedayan root infusion (Aristolochia sp.) using brine shrimp lethality test method

نویسندگان

چکیده

Kedayan roots are still used by the Lundayeh Dayak people as traditional medicine. This plant is one of Aristolochia sp . species whose production and distribution medicine or food supplements prohibited Food Drug Supervisory Agency Republic Indonesia because it has side effects that harmful to body. The purpose this study was determine toxicity kedayan root infusion using Brine Shrimp Lethality Test (BSLT) method based on LC50 value. Toxicity test carried out varying concentration infusion, namely 100, 500, 1000 ppm, an intervention against Artemia salina Leach with a negative control in form 2.8% saline solution for 24 hours 3 replications, then observing presence absence movement s alina L. Larvae. results data % mortality obtained, analyzed probit regression analysis indicate very high toxicity, value 101.9278 ppm.

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Lethality Assay of Radiopharmaceutical bis-Thiosemicarbazones Using Brine Shrimp (Artemia salina) Test

      In the present study, aqueous solutions of some copper-complexing ligands were screened for their cytotoxicity using brine shrimp lethality test. Among the ligands tested, diacetyl-bis(N4-methylthiosemicarbazones) (ATSM) proved to be the most safe and non-toxic compound (2% lethality at 10 ppm), while pyruvaldehyde Bis(N4-methyl)thiosemicarbazone (P...

متن کامل

lethality assay of radiopharmaceutical bis-thiosemicarbazones using brine shrimp (artemia salina) test

in the present study, aqueous solutions of some copper-complexing ligands were screened for their cytotoxicity using brine shrimp lethality test. among the ligands tested, diacetyl-bis(n4-methylthiosemicarbazones) (atsm) proved to be the most safe and non-toxic compound (2% lethality at 10 ppm), while pyruvaldehyde bis(n4-methyl)thiosemicarbazone (ptsm) was shown to possess low toxicity (7% let...

متن کامل

Antioxidant, antibacterial activity and brine shrimp toxicity test of some mountainous lichens from Nepal.

A total of twenty four lichen species belonging to six families were collected from mountainous region of Nepal. The methanol extracts of each species were tested for antimicrobial and antioxidant activities in vitro. It was found that extracts of twenty one lichen species were active against B. subtilis and seven species were active against S. aureus. Similarly, in DPPH assay, three species Pe...

متن کامل

Acute Oral Toxicity and Brine Shrimp Lethality of Methanol Extract of Mentha Spicata L (Lamiaceae)

Purpose: To determine, in Sprague Dawley rats, the toxicity profile of the methanol extract of Mentha spicata, a plant used in folklore medicine for the treatment of various forms of pain. Methods: The plant extract, at concentrations ranging from 100 0.07 mg/ml, was used to determine the median lethal concentration (LC50) based on brine shrimp lethality assay. Artificial sea water served as co...

متن کامل

Acute oral toxicity and brine shrimp lethality of Elaeis guineensis Jacq., (oil palm leaf) methanol extract.

Elaeis guineensis (Arecaceae) is widely used in West African traditional medicine for treating various ailments. An evaluation on the toxicity of extracts of this plant is crucial to support the therapeutic claims. The acute oral toxicity and brine shrimp lethality of a methanolic extract of this plant was tested. Oral administration of crude extract at the highest dose of 5,000 mg/kg resulted ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Media Farmasi: Jurnal Ilmu Farmasi

سال: 2022

ISSN: ['2503-5223', '1412-7946']

DOI: https://doi.org/10.12928/mf.v19i2.21045